Assessment of risk factors for in-hospital mortality after intensive care unit discharge

Ins Arajo, João Gonçalves-Pereira, Sofia Teixeira, Raquel Nazareth, Joana Silvestre, Vtor Mendes, Camila Tapadinhas, Pedro Póvoa

Research output: Contribution to journalArticlepeer-review

13 Citations (Scopus)

Abstract

Context: Post-intensive care unit (ICU) mortality predictors are unknown. Objective: To assess post-ICU in-hospital mortality predictors. Materials and methods: Analysis of 296 patients discharged alive from a medical-surgical ICU during an 18-month period. Results: Post-ICU in-hospital mortality was 22.6%. Nonsurvivors had significantly higher Charlson comorbidity score and more often had a tracheostomy. C-reactive protein (CRP) "alert measurement", ≥ 6mg/dL, independently discriminated survivors from nonsurvivors. Discussion: A CRP "alert measurement" or the need for tracheostomy may be used to identify patients with high risk of dying after ICU discharge. Conclusions: Charlson comorbidity score, CRP and tracheostomy predicted post-ICU in-hospital mortality.

Original languageEnglish
Pages (from-to)180-185
Number of pages6
JournalBiomarkers
Volume17
Issue number2
DOIs
Publication statusPublished - Mar 2012

Keywords

  • C-reactive protein
  • Charlson comorbidity score
  • ICU patient discharge
  • Mortality
  • Tracheostomy

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