Renal denervation for resistant hypertension

Research output: Contribution to journalArticlepeer-review

3 Citations (Scopus)

Abstract

There is a marked contrast between the high prevalence of hypertension and the low rates of adequate control. A subset of patients with suboptimal blood pressure control have drug-resistant hypertension, in the pathophysiology of which chronic sympathetic hyper-activation is significantly involved. Sympathetic renal denervation has recently emerged as a device-based treatment for resistant hypertension. In this review, the pathophysiological mechanisms linking the sympathetic nervous system and cardiovascular disease are reviewed, focusing on resistant hypertension and the role of sympathetic renal denervation. An update on experimental and clinical results is provided, along with potential future indications for this device-based technique in other cardiovascular diseases. (C) 2014 Sociedade Portuguesa de Cardiologia. Published by Elsevier Espana, S.L.U. All rights reserved.
Original languageUnknown
Pages (from-to)125-135
JournalRevista Portuguesa de Cardiologia
Volume34
Issue number2
DOIs
Publication statusPublished - 1 Jan 2015

Keywords

  • Cardiac & Cardiovascular Systems

Cite this